Roger Federer has crashed out of the Cincinnati Masters.
The seven time winner suffered a shock straights sets defeat to 21-year-old Russian qualifier Andrey Rublev.
The third round win means Rublev will now face compatriot Daniil Medvedev in the quarter-finals.
Meanwhile world number one Novak Djokovic is through to the final eight after an easy win over Pablo Carreño Busta.