Iran's consulate in the Syrian capital Damascus was flattened on Monday in what Syrian and Iranian media described as an Israeli air strike.
A Lebanese security source, speaking to Reuters, said one of the dead was Mohammad Reza Zahedi, a senior commander in Iran's Revolutionary Guards Corps (IRGC). Iranian state television said several Iranian diplomats had been killed.
Israel, which has repeatedly hit Iranian targets during the six-month war in Gaza, declined to comment on the incident, following its usual practice.
An Israeli military spokesperson said: "We do not comment on reports in the foreign media."
Iran's Tasnim news agency said five people were killed in the Israeli strike. Syria's SANA state news agency reported an unspecified number of deaths and injuries.
Since the Palestinian group Hamas' attack on Israel on October 7, Israel has ramped up airstrikes in Syria against Lebanon's Hezbollah militia and Iran's Guards, both of which support the government of President Bashar Al Assad.
United Nations Secretary-General Antonio Guterres has rejected a new Israeli proposal to control aid deliveries in Gaza, saying it risks "further controlling and callously limiting aid down to the last calorie and grain of flour".
A catastrophic roof collapse at a nightclub in the Dominican Republic's capital left at least 79 people dead on Tuesday and emergency crews were working frantically after nightfall to pull survivors from the rubble.
At least 50 hippos and other large animals have been killed by anthrax poisoning in eastern Congo's Virunga National Park and have been spotted floating along a major river that feeds one of Africa's great lakes, the head of the park said on Tuesday.
Former Russian president Dmitry Medvedev said on Tuesday that more countries would get nuclear weapons in the coming years, blaming the West for pushing the world towards the brink of World War Three by waging a proxy war against Russia in Ukraine.