Gunmen stormed a home in a township outside the South African city of Pietermaritzburg and killed 10 members of the same family, police have said.
Police did not give a motive for the shooting.
Seven women and three men were killed, the police ministry said in a statement.
South Africa has one of the world's highest murder rates, with about 20,000 murders recorded every year out of a population of 60 million.
"It's a crime scene, terrible. Too many people were lost here," Police Minister Bheki Cele said in comments broadcast on public broadcaster SABC from Pietermaritzburg in KwaZulu-Natal province.
Cele said police management needed to sit down to talk about whether the province needed more police resources.
A Reuters photojournalist at the scene of the shooting saw a mortuary van in the yard of the homestead into which bodies of those killed were being loaded on a stretcher. Worried members of the community looked on.
A preliminary report depicted confusion in the cockpit shortly before an Air India jetliner crashed, killing 260 people last month, after the plane's engine fuel cutoff switches almost simultaneously flipped, starving the engines of fuel.
US President Donald Trump defended the state and federal response to deadly flash flooding in Texas on Friday as he visited the stricken Hill Country region, where at least 120 people, including dozens of children, perished a week ago.
Russia pounded Ukraine with hundreds of drones and dozens of missiles on Saturday, in the fourth major attack this month, targeting western cities and killing at least two people in Chernivtsi on the border with Romania.
Thirty Kurdistan Workers Party (PKK) fighters burned their weapons at the mouth of a cave in northern Iraq on Friday, marking a symbolic but significant step toward ending a decades-long armed conflict against Turkey.